CELE_VF13D12L.1, VF13D12L.1

inos-1 encodes the C. elegans myo-inositol-1-phosphate (MIP) synthase ortholog; by homology, the product of inos-1 is predicted to function in de novo inositol biosynthesis by catalyzing the conversion of glucose-6-phosphate to inositol-1-phosphate; loss of inos-1 activity via RNAi has been reported to result in low levels of embryonic lethality, larval lethality, slow growth, uncoordinated locomotion, and a substantial increase in fat content; loss of inos-1 activity also results in a slight increase in the variability of the defecation cycle length, although this increase is not statistically significant; in situ hybridization studies reveal that inos-1 mRNA is expressed faintly in the germline.

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