Caenorhabditis elegans
PAT-3
CELE_ZK1058.2, epi-2, INTB/1, ZK1058.2
pat-3 encodes the C. elegans beta-integrin subunit; pat-3 is an essential gene that is required for muscle cell attachment to the overlying hypodermis and for normal muscle filament assembly and function; in addition, pat-3 is required for normal axon guidance and for ovulation; antibody staining reveals that PAT-3 is expressed in body wall muscle as well as in the anal depressor, sphincter, intestinal, vulval, and uterine muscles and the somatic gonad; PAT-3 localizes to dense bodies, M-lines, and intercellular borders.
GO Process (10)
GO Function (1)
GO Component (6)
Gene Ontology Biological Process
- apoptotic process [IMP]
- cell migration [IMP]
- embryo development ending in birth or egg hatching [IMP]
- inductive cell migration [IMP]
- locomotion [IMP]
- muscle cell development [IMP]
- positive regulation of locomotion [IMP]
- protein catabolic process [IMP]
- reproduction [IMP]
- striated muscle contraction involved in embryonic body morphogenesis [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Download Curated Data for this Protein
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- Interactors 20
- Interactions 24
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