Caenorhabditis elegans
RNF-5
CELE_C16C10.7, C16C10.7
rnf-5 encodes a homolog of mammalian RNF5, an E3 ubiquitin ligase; in C. elegans, RNF-5 functions as a ubiquitin ligase that regulates activity of the UNC-95 LIM domain protein that is essential for proper formation of muscle attachment structures; RNF-5 is also required for distal tip cell migration (DTC) and genetic interactions suggest that RNF-5 functions at least partially in parallel with the coiled-coil domain protein CCDC-55 and the E3 ubiquitin ligase RNF-121 to regulate DTC migration; RNF-5 localizes to striated muscle dense bodies, cell junctions, and to the nucleus.
GO Process (6)
GO Function (3)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
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40769
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- Interactors 3
- Interactions 4
- Network