Caenorhabditis elegans
MMAB-1
CELE_C26E6.11, tag-339, C26E6.11
mmab-1 encodes an ortholog of human co(I)balamin adenosyltransferase (MMAB); mmab-1 deletion mutants incorporate abnormally low levels of 1-[(14)C]-propionate into proteins; mmab-1 mutants and mmab-1(RNAi) animals excrete abnormally high levels of methylmalonic acid into their culture medium when challenged with propionic acid; these data are consistent with the hypothesis that MMAB-1 participates in the conversion of propionyl-CoA to succinyl-CoA.
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