CELE_ZC395.6, ZC395.6

gro-1 encodes two isoforms of the C. elegans isopentenylpyroptiosphate:tRNA transferase (IPT) ortholog; by homology, GRO-1 is predicted to function in modification of a subset of tRNAs; in C. elegans, a loss-of-function mutation in gro-1 results in delayed embryogenesis and postembryonic development, slower rates of adult behaviors, reduced brood size, and a genetic background-specific increase in adult life span; gro-1's effect on embryonic development exhibits a strict maternal effect; GRO-1::GFP fusion proteins are widely expressed and localize to the cytoplasm, nucleus, and mitochondria.

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