Caenorhabditis elegans

UPP-1

CELE_ZK783.2, ZK783.2
upp-1 encodes the C. elegans uridine phosphorylase ortholog; loss of upp-1 activity results in resistance to the anticancer pyrimidine analog 5-fluorouracil (5-FU); in vitro, UPP-1 exhibits both uridine and thymidine phosphorylase activity.
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  • Interactors 28
  • Interactions 28
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