ceh-26, CELE_K12H4.1, K12H4.1

pros-1 encodes a homeodomain protein that is the C. elegans homolog of Drosophila prospero and mammalian Prox1 (Prospero-related homeobox); loss of pros-1 function in large-scale RNAi screens has been reported to result in locomotion defects, slow growth, and larval lethality; a pros-1::gfp reporter fusion is expressed beginning at the comma stage of embryogenesis and continues through adulthood; pros-1::gfp expression is seen mainly in head and tail neurons and in the excretory cell; male-specific expression is seen in the HOB hook neuron where it is positively regulated by the EGL-46 and EGL-44 transcription factors, as well as the DAF-19 RFX transcription factor.

41343

6239