Caenorhabditis elegans
HPD-1
CELE_T21C12.2, T21C12.2
hpd-1 encodes a putative 4-hydroxyphenylpyruvate dioxygenase required for normally short lifespan and for negative regulation of the dauer larval stage, with loss of hpd-1 function prolonging lifespan and promoting dauer formation; hpd-1 is a (perhaps evolutionarily conserved) target of transcriptional activation by DAF-16; HPD-1 is orthologous to human HPD (OMIM:609695, mutated in tyrosinemia type III), and is paralogous to C31H2.4 and human HPDL/GLOXD1; HPD-1 is expressed in hypodermis and intestine, and is required for the tyrosinemic phenotype of K10C2.4(RNAi) animals.
GO Process (2)
GO Function (1)
GO Component (0)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Download Curated Data for this Protein
41664
6239
Switch View:
- Interactors 12
- Interactions 12
- Network