Caenorhabditis elegans

RSP-3

CELE_Y111B2A.18, CeSF2/ASF, CeSF2, Y111B2A.18
rsp-3 encodes an ortholog of human SF2/ASF and member of the SR protein family of nuclear phosphoproteins that are required for constitutive splicing and influence alternative splicing regulation; rsp-3 affects the development of oocytes together with rsr-1, and is required for late embryonic viability; SPK-1 binds directly to and phosphorylates the RS domain of RSP-3 in vitro; the rsp-3 mRNA is predominantly expressed in the germline.
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  • Interactors 41
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