Caenorhabditis elegans
EFN-4
CELE_F56A11.3, mab-26, F56A11.3
efn-4 encodes a divergent member of the ephrin family of ligands; efn-4 is required for neuroblast migrations during closure of the ventral gastrulation cleft and subsequent epidermal morphogenesis, possibly functioning independently of EFN-1, EFN-2, EFN-3, and the VAB-1 receptor during morphogenesis; EFN-4 can interact weakly with VAB-1 in vitro; EFN-4 is expressed in neural and epidermal precursors at the 100-cell stage, in head neurons, pharyngeal cells, lateral and tail neurons, and in the ectoderm during epidermal enclosure.
GO Process (8)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
- axon guidance [IBA]
- cell migration involved in gastrulation [IGI, IMP]
- embryo development ending in birth or egg hatching [IGI, IMP]
- ephrin receptor signaling pathway [IBA]
- morphogenesis of embryonic epithelium [IGI, IMP]
- nematode male tail tip morphogenesis [IGI, IMP]
- regulation of cell adhesion [IGI, IMP]
- reproduction [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Download Curated Data for this Protein
42043
6239
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- Interactors 6
- Interactions 9
- Network