CELE_Y73B6BL.19, Y73B6BL.19

shl-1 encodes a SHAL/Kv4 ortholog, which encodes voltage-gated potassium channels expressed in muscle; mutations in shl-1 result in loss of all fast transient outward current from muscle cells and, in males, reduced mating efficiency owing to difficulty in locating the hermaphrodite vulva; when expressed in Xenopus oocytes or cultured myocytes, SHL-1 exhibits currents; an SHL-1::GFP reporter fusion is expressed in posterior intestine, body wall muscle, vulval muscle, male-specific diagonal muscles, and a number of motor neurons, interneurons, and sensory neurons.

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