Caenorhabditis elegans

ANT-1.4

CELE_T01B11.4, ant-1.44, tag-316, wan-3, T01B11.4
ant-1.4 encodes an ortholog of the human adenine nucleotide translocase ANT genes, the other ANT genes in C. elegans include ant-1.1, ant-1.2 and ant-1.3; phylogenetic analysis indicates that ant-1.4 is specific to C. elegans, resulting from a recent duplication following the speciation of the common ancestor of C. elegans, C. briggsae, and C. remanei; by homology, ANT-1.4 is predicted to mediate the exchange of ATP generated in the mitochondria for cytosolic ADP; ANT-1.4 GFP fusion protein is expressed in a pair of head neurons, amphid socket and sheath cells and in a few body-wall muscle and vulval muscle cells.
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