CELE_ZC168.1, ZC168.1

ncx-3 encodes a putative 3Na[+]/1Ca[2+] exchanger, orthologous to human SLC8A1-3 and paralogous to NCX-1/-2; NCX-3 is predicted to export free cytoplasmic Ca[2+] with low affinity but high capacity, being complemented by low-capacity/high-affinity Ca[2+] ATPase pumps such as MCA-1/-3; NCX-3 has tandem Calx-alpha and Calx-beta domains predicted to carry out ion transport and regulation; NCX-3 has no obvious function in mass RNAi assays.

43064

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