CELE_R09A1.1, eri-8, R09A1.1

ergo-1 encodes an Argonaute protein; ERGO-1 is required for somatic gene regulation via the production or stabilization of endogenous (endo)-siRNAs, specifically the initial class of endo-siRNAs which are 26-nt, 5'-monophosphorylated, 5'-G-enriched antisense siRNAs; ERGO-1 activity is also required for the subcellular redistribution of the NRDE-3 Argonaute protein which, upon binding secondary siRNAs, translocates from the cytoplasm to the nucleus.

43674

6239