CELE_F16B3.1, F16B3.1

egl-2 encodes a voltage-gated potassium channel that is the C. elegans homolog of ether-a-go-go (EAG); egl-2 activity is required for egg laying, muscle activation, defecation, mechanosensation, and chemosensation; egl-2 is expressed in the intestinal muscle, AFD, ALN, AQR, ASE, AWC, BAG, IL2, PLN, PQR, and URX neurons as well as a subset of sensory neurons in the male tail; EGL-2 activity can be regulated by the UNC-43 calcium/calmodulin-dependent protein kinase II (CaMKII) with which it interacts physically.

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