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Caenorhabditis elegans

AIR-1

CELE_K07C11.2, let-412, K07C11.2

AIR-1 belongs to the Aurora-A family of serine/threonine kinases that localize to centrosomes; AIR-1 is required for embryonic survival, germline proliferation and development, locomotion, and vulval development; AIR-1 is required to recruit centrosomal gamma-tubulin during maturation; Aurora-A kinases are implicated in centrosome separation and spindle assembly.

GO Process (6)

GO Function (2)

GO Component (5)

Gene Ontology Biological Process

apoptotic process [IMP]

embryo development ending in birth or egg hatching [IMP]

microtubule nucleation [IMP]

protein phosphorylation [IDA]

reproduction [IMP]

spindle assembly involved in mitosis [IMP]

Gene Ontology Molecular Function

protein binding [IPI]
protein kinase activity [IDA]

Gene Ontology Cellular Component

astral microtubule [IDA]

centrosome [IDA]

condensed nuclear chromosome [IDA]

kinetochore microtubule [IDA]

spindle pole centrosome [IDA]

WormBase Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

44244

6239

Interactors 22
Interactions 30
Network