Caenorhabditis elegans
MOM-2
CELE_F38E1.7, F38E1.7
mom-2 encodes a member of the Wnt family of secreted signaling glycoproteins that is required for induction of endodermal (gut) tissue in the 4-cell stage embryo; MOM-2, required in the inducing blastomere (P2) at the 4-cell stage, may be the ligand for MOM-5, a Frizzled homolog, thought to act in the receiving blastomere (EMS); MOM-2 genetically interacts in the same pathway as KIN-19, but parallel to APR-1; MOM-2 also may be a ligand for LIN-18, a Ryk homolog.
GO Process (12)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
- RNA interference [IMP]
- Wnt signaling pathway [IBA, ISS]
- asymmetric protein localization involved in cell fate determination [IMP]
- body morphogenesis [IMP]
- embryo development ending in birth or egg hatching [IMP]
- embryonic morphogenesis [IMP]
- endodermal cell fate specification [IGI, IMP]
- establishment of cell polarity [IMP]
- establishment of mitotic spindle orientation [IGI, IMP]
- nematode larval development [IMP]
- neuron differentiation [IBA]
- reproduction [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Download Curated Data for this Protein
44258
6239
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- Interactors 35
- Interactions 40
- Network