CELE_F07C3.4, F07C3.4

glo-4 encodes a guanine nucleotide exchange factor (GEF) that is similar to Drosophila Claret and human RP3; throughout development, glo-4 activity is required for biogenesis of the lysosome-related gut granules; based upon phenotypic similarity, glo-4 is likely to encode a GEF for the GLO-1 Rab-like GTPase; in regulating gut granule formation, glo-4 acts downstream of apb-3, which encodes the AP-3 complex beta subunit.

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