Caenorhabditis elegans

RDE-1

CELE_K08H10.7, K08H10.7
rde-1 encodes a novel, conserved protein that is a member of the PIWI/STING/Argonaute/Zwille/eIF2c family of proteins; rde-1 activity is required for RNA-mediated interference (RNAi), specifically for removal of the passenger strand from siRNAs during siRNA maturation; RDE-1 interacts with RDE-4 in vivo and its activity is also required for accumulation of dsRNA bound to RDE-4.
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  • Interactors 9
  • Interactions 11
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