Caenorhabditis elegans
ACT-2
CELE_T04C12.5, act2, T04C12.5
act-2 encodes one of five C. elegans actins; act-2 functions redundantly in early embryonic cortical microfilaments with act-1 and act-3, and dominant mutations in act-2 result in uncoordinated locomotion; an ACT-2::GFP reporter fusion is expressed in the cytoplasm of embryonic cells and is also found in contractile filaments in adult muscle cells.
GO Process (17)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
- ATP catabolic process [ISS]
- actin cytoskeleton organization [IMP]
- actin filament-based process [IMP]
- cytokinesis [IMP]
- cytokinesis, initiation of separation [IMP]
- embryo development [IGI, IMP]
- embryo development ending in birth or egg hatching [IMP]
- growth [IMP]
- hermaphrodite genitalia development [IMP]
- inductive cell migration [IMP]
- locomotion [IMP]
- meiotic nuclear division [IMP]
- mitotic cytokinesis [IGI]
- nematode larval development [IMP]
- receptor-mediated endocytosis [IMP]
- reproduction [IMP]
- striated muscle myosin thick filament assembly [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
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- Interactors 58
- Interactions 60
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