Caenorhabditis elegans


CELE_H37A05.1, H37A05.1
lpin-1 encodes a putative phosphatidic acid phosphatase orthologous to budding yeast PAH1 and human LPIN1 (OMIM:605518), LPIN2 (OMIM:605519, mutated in Majeed syndrome), and LPIN3 (OMIM:605520); lpin-1 is expressed in vulval muscle; in mass RNAi assays, lpin-1 is required for the osmotic integrity of eggs and for normal larval growth, body thickness, locomotion, and fertility; by orthology, LPIN-1 is expected to be dephosphorylated by SCPL-2.

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WormBase | Entrez Gene | RefSeq | UniprotKB
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