Caenorhabditis elegans


CELE_F53C11.8, F53C11.8
swan-1 encodes a protein that belongs to the family of AN11 WD repeat proteins; WD repeats are considered to form a scaffold for protein-protein interactions; SWAN-1 was initially identified as a protein that interacts with UNC-115 and the RAC proteins-CED-10, MIG-2 and RAC-2; genetic interaction studies with the Rac genes indicate that swan-1 is a negative regulator of Rac GTPase function during morphogenesis and phagocytosis of apoptotic cells; swan-1 is expressed in most cells throughout development and is predominant in the cytoplasm.
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  • Interactors 7
  • Interactions 10
  • Network