Caenorhabditis elegans

EFL-1

CELE_Y102A5C.18, mex-2, Y102A5C.18
efl-1 encodes a homolog of mammalian E2F that is required for embryonic asymmetry and that functions as a transcriptional repressor; during vulval development, efl-1, a class B synMuv gene, acts with class B synMuv genes dpl-1 and lin-35/Rb to antagonize receptor tyrosine kinase and Ras-mediated signaling; EFL-1 also negatively regulates the G1 to S phase cell cycle transition.

External Database Linkouts

WormBase | Entrez Gene | RefSeq | UniprotKB
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