Caenorhabditis elegans


CELE_Y59A8A.1, Y59A8A.1
csn-1 encodes an ortholog of subunit 1 of the COP9 signalosome complex (CSN1), which in turn is a pan-eukaryotic multiprotein complex that positively regulates E3 ubiquitin ligases, physically interacts with SCF-type E3 ubiquitin ligases, and probably regulates protein degradation; in mass RNAi assays, csn-1 is required for embryonic viability, maintenance of the germline, and general health.
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  • Interactors 24
  • Interactions 33
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