Caenorhabditis elegans


CELE_Y60A3A.12, Ce-cds-1, Ce-chk-2, cds-1, Y60A3A.12
chk-2 encodes a member of the Cds1/Chk2 checkpoint kinase family, orthologous to human CHK2 (OMIM:604373, mutated in Li-Fraumeni syndrome), that affects pairing between homologous chromosomes during early meiotic prophase, and might function to couple premeiotic S phase with early prophase; CHK-2 is expressed in the germ line.
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  • Interactors 5
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