Caenorhabditis elegans

SEC-23

CELE_Y113G7A.3, Y113G7A.3
sec-23 encodes a component of COPII (coat protein complex II)-coated vesicles orthologous to Saccharomyces cerevisiae Sec23p; by homology, SEC-23 is predicted to be involved in endoplasmic reticulum (ER)-to-Golgi transport; loss of sec-23 activity results in defects in oogenesis, morphogenesis, and extracellular matrix secretion; a SEC-23::GFP fusion protein localizes to the apical region of the endoplasmic reticulum of hypodermal cells, consistent with localization to endoplasmic reticulum exit sites.
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  • Interactors 23
  • Interactions 27
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