Caenorhabditis elegans


CELE_Y113G7B.17, epg-11, Y113G7B.17
prmt-1 encodes a type I protein arginine methyltransferase; in C. elegans, PRMT-1 positively regulates adult lifespan and is required for stress response and fat storage in the absence of DAF-2-mediated signaling; PRMT-1 is also required for proper development of myofilament structure; PRMT-1 physically interacts with, and methylates, DAF-16 thereby preventing its phosphorylation and cytoplasmic retention; in body wall muscle cells, PRMT-1 has been localized to the endoplasmic reticulum.
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  • Interactors 38
  • Interactions 41
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