Caenorhabditis elegans
PTR-4
CELE_C45B2.7, C45B2.7
ptr-4 encodes a nematode-specific member of the sterol sensing domain (SSD) proteins, distantly paralogous to Drosophila PATCHED (PTC) and human PTCH (OMIM:601309, mutated in basal cell nevus syndrome); PTR-4 is strongly required for normal molting from L4 to adult stages male tail development (a role conserved in C. briggsae); PTR-4 is also required for normal endocytosis of yolk by oocytes, adult alae formation, growth to full size, locomotion, and viability.
GO Process (10)
GO Function (0)
GO Component (0)
Gene Ontology Biological Process
- body morphogenesis [IMP]
- embryo development ending in birth or egg hatching [IMP]
- endocytosis [IMP]
- engulfment of apoptotic cell [IMP]
- locomotion [IMP]
- molting cycle, collagen and cuticulin-based cuticle [IMP]
- nematode larval development [IMP]
- nematode male tail tip morphogenesis [IMP]
- positive regulation of multicellular organism growth [IMP]
- reproduction [IMP]
Download Curated Data for this Protein
45808
6239
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- Interactors 3
- Interactions 3
- Network