Caenorhabditis elegans
PEPT-1
CELE_K04E7.2, opt-2, pep-2, K04E7.2
pept-1 encodes a low affinity/high capacity oligopeptide transporter; pept-1 is required for uptake of intact peptides from the intestine and thus for normal development, growth, and reproduction; genetic studies indicate that pept-1 interacts with both the daf-2/insulin- and let-363/TOR-signaling pathways to regulate lifespan and with the daf-2 pathway to influence stress response; PEPT-1 is expressed in the intestine where it localizes to the apical membrane.
GO Process (15)
GO Function (1)
GO Component (1)
Gene Ontology Biological Process
- amino acid homeostasis [IMP]
- determination of adult lifespan [IGI, IMP]
- dipeptide transport [IMP]
- lipid metabolic process [IMP]
- lipid storage [IMP]
- negative regulation of fatty acid transport [IMP]
- nematode larval development [IGI, IMP]
- positive regulation of growth rate [IGI, IMP]
- positive regulation of multicellular organism growth [IMP]
- regulation of TOR signaling [IMP]
- regulation of endoplasmic reticulum unfolded protein response [IMP]
- regulation of pH [IGI]
- reproduction [IGI, IMP]
- response to heat [IGI, IMP]
- response to oxidative stress [IGI, IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Download Curated Data for this Protein
45849
6239
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- Interactors 6
- Interactions 6
- Network