Caenorhabditis elegans

DPY-22

CELE_F47A4.2, mdt-12, psa-6, sop-1, F47A4.2
dpy-22 encodes a broadly expressed protein, homologous to the human transcriptional mediator protein TRAP230, which is involved in WNT and RAS signaling, as well as in dosage compensation; DPY-22 has a C-terminal glutamine-rich domain that is dispensable for inhibition of RAS-dependent cell differentiation, but is required for inhibition of BAR-1-dependent gene expression.
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  • Interactors 20
  • Interactions 21
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