Caenorhabditis elegans
DPY-22
CELE_F47A4.2, mdt-12, psa-6, sop-1, F47A4.2
dpy-22 encodes a broadly expressed protein, homologous to the human transcriptional mediator protein TRAP230, which is involved in WNT and RAS signaling, as well as in dosage compensation; DPY-22 has a C-terminal glutamine-rich domain that is dispensable for inhibition of RAS-dependent cell differentiation, but is required for inhibition of BAR-1-dependent gene expression.
GO Process (11)
GO Function (0)
GO Component (0)
Gene Ontology Biological Process
- body morphogenesis [IMP]
- embryo development ending in birth or egg hatching [IMP]
- hermaphrodite genitalia development [IMP]
- locomotion [IMP]
- molting cycle, collagen and cuticulin-based cuticle [IMP]
- negative regulation of vulval development [IMP]
- nematode larval development [IMP]
- oviposition [IMP]
- positive regulation of multicellular organism growth [IMP]
- positive regulation of vulval development [IMP]
- reproduction [IMP]
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46109
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- Interactors 21
- Interactions 22
- Network