Caenorhabditis elegans


CELE_C44H4.5, C44H4.5
tap-1 encodes the C. elegans ortholog of the vertebrate TAB1 (TGF-beta activated kinase 1/MAP3K7 binding protein 1) protein; tap-1 is required, together with mom-4, for endodermal cell fate specification in the developing embryo; when co-expressed in vitro, TAP-1 binds MOM-4, the C. elegans TAK1 ortholog, and positively regulates MOM-4 MAPKKK activity.
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  • Interactors 15
  • Interactions 20
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