Caenorhabditis elegans
LIN-15B
CELE_ZK662.4, lin-15, ZK662.4
lin-15B encodes a novel protein that contains a THAP domain, a zinc-coordinating, site-specific DNA-binding domain; lin-15B was first identified as a class B synMuv gene that acts redundantly with lin-15A to negatively regulate the outcome of Ras signaling during vulval cell fate specification; subsequently, lin-15B has been shown to also negatively regulate progression through the G1 phase of the cell cycle and RNA-mediated interference (RNAi).
GO Process (7)
GO Function (0)
GO Component (1)
Gene Ontology Biological Process
- embryo development ending in birth or egg hatching [IMP]
- endoplasmic reticulum unfolded protein response [IEP]
- negative regulation of Ras protein signal transduction [IMP]
- negative regulation of vulval development [IGI, IMP]
- nematode larval development [IMP]
- positive regulation of vulval development [IMP]
- regulation of cell fate specification [IMP]
Download Curated Data for this Protein
46554
6239
Switch View:
- Interactors 17
- Interactions 17
- Network