Caenorhabditis elegans

OSM-1

CELE_T27B1.1, T27B1.1
osm-1 encodes a WD- and WAA-repeat containing protein that is the C. elegans ortholog of intraflagellar transport (IFT) complex B component IFT172; OSM-1 is a presumptive cargo molecule for kinesin-II, and OSM-1 is required, along with OSM-6, for the proper assembly of the middle segments of sensory cilia; osm-1 may act in a pathway with avr-14 to affect resistance to ivermectin-induced cessation of pumping, and mutants are defective in avoidance of solutions of high osmotic strength; an OSM-1::GFP fusion protein is expressed in amphid and phasmid chemosensory neurons where it undergoes both anterograde and retrograde intraflagellar transport.
GO Process (2)
GO Function (0)
GO Component (6)

External Database Linkouts

WormBase | Entrez Gene | RefSeq | UniprotKB
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  • Interactors (2)
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