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Caenorhabditis elegans

MEC-4

CELE_T01C8.7, mec-13, T01C8.7

mec-4 encodes an amiloride-sensitive Na+ channel protein (degenerin) required to sense gentle mechanical stimuli (e.g. touch) along the body wall; MEC-4 is paralogous to, and coexpressed with, MEC-10, in all six touch cell neurons where they form a heteromeric mechanotransduction channel.

GO Process (4)

GO Function (1)

GO Component (2)

Gene Ontology Biological Process

mechanosensory behavior [IMP]

negative regulation of turning behavior involved in mating [IMP]

response to mechanical stimulus [IMP]

sodium ion transmembrane transport [IDA]

Gene Ontology Molecular Function

ligand-gated sodium channel activity [IDA]

Gene Ontology Cellular Component

integral component of plasma membrane [IDA]

neuron projection membrane [IDA]

WormBase Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

46611

6239

Interactors 8
Interactions 21
Network