CELE_C36E6.5, C36E6.5

mlc-2 encodes, along with mlc-1 and mlc-4, one of three C. elegans regulatory myosin light chains; MLC-2 is predicted to function as a regulator of myosin ATPase activity, and genetic studies indicate that MLC-2 is nearly essential in hermaphrodites for normal pharyngeal muscle function, but redundant with MLC-1, with which it is nearly identical, for proper bodywall muscle development; accordingly, loss of mlc-2 activity eventually results in larval lethality, as animals are not able to feed properly; mlc-2 mRNA is expressed in bodywall, pharyngeal, and vulval muscles.

46650

6239