Caenorhabditis elegans
TBX-38
CELE_C24H11.3, C24H11.3
tbx-38 encodes a T box transcription factor; during embryonic development, tbx-38 functions redundantly with tbx-37 to effect Notch-mediated pharyngeal mesoderm induction in descendants of the ABa blastomere; in addition, tbx-38 and tbx-37 are required for proper cell fate specification of other ABa descendants, such as those that give rise to hypodermal tissue; TBX-38 expression appears to be limited to the 8 ABa descendents at the 24-cell stage of embryogenesis, with expression diminishing markedly during the next cell cycle; negative regulation of TBX-38 expression in ABp descendants depends upon Notch signaling, while negative regulation of expression in EMS descendents is likely controlled, in part, by ref-1 and unc-37, which encode bHLH and Groucho-like proteins, respectively.
GO Process (1)
GO Function (1)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
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- Interactors 8
- Interactions 9
- Network