CELE_F46F11.4, F46F11.4

ubl-5 encodes a ubiquitin-like protein orthologous to human ubiquitin-like protein UBL5; UBL-5 activity is required for normal mitochondrial morphology as well as for assembly of mitochondrial multi-protein complexes; in addition, UBL-5 is essential for the mitochondrial unfolded protein response (UPRmt); in adult animals, ubl-5 is expressed at low levels in most tissues, with slightly higher levels seen in the intestine, particularly the posterior region, and the pharynx; UBL-5 localizes to the cytosol and to the nucleus, with nuclear levels increased upon induction of the UPRmt.

50630

6239