Caenorhabditis elegans

CPAR-1

CELE_F54C8.2, F54C8.2
cpar-1 encodes one of two C. elegans proteins homologous to the inner kinetochore histone H3 variant CENP-A (the other is encoded by hcp-3); loss of cpar-1 and hcp-3 activity via RNAi results in mitotic chromosome segregation defects, but no significant defects in meiotic chromosome segregation; when expressed in the germline using the pie-1 promoter, a CPAR-1::GFP fusion protein localizes to meiotic chromosomes during late prophase/prometaphase of meiosis I, but is not seen on chromosomes during meiosis II.
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  • Interactors 4
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