CELE_K03E6.4, tza-2, K03E6.4

mkrs-1 encodes an ortholog of human B9D1, paralogous to MKRS-2 and MKS-1; MKRS-1 is required for fully normal foraging behavior, and is redundantly required with NPH-4 for roughly normal foraging, and with both NPH-1 and NPH-4 for cilia formation; mkrs-1 is expressed generally in neurons throughout the body, with ciliary neuron expression being dependent on DAF-19; MKRS-1 forms a complex with MKRS-2 and MKS-1 at the base of cilia, and is coexpressed with these proteins in ciliated sensory neurons; MKRS-1 requires MKRS-2 for localization to the transistion zone, and binds MKRS-2 in two-hybrid assays.

51662

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