CELE_R04F11.1, R04F11.1

hpo-30 encodes a claudin homolog that may be required for normal cohesion of apical junctions in epithelia; hpo-30 is worm-specific, with obvious homologs only in C. elegans; claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water.

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