Caenorhabditis elegans

DAF-8

CELE_R05D11.1, smad-1, R05D11.1

daf-8 encodes a Smad protein that represses dauer development, perhaps by antagonizing DAF-3 activity, and promotes a commitment to reproductive growth; genetic interactions suggest partial functional redundancy with daf-14 with respect to the TGF-beta signaling pathway that regulates dauer formation.

GO Process (5)

GO Function (1)

GO Component (2)

Gene Ontology Biological Process

dauer larval development [IGI, IMP]

negative regulation of transcription from RNA polymerase II promoter [IMP]

oviposition [IGI]

pigment accumulation [IGI]

positive regulation of transcription from RNA polymerase II promoter [IMP]

Gene Ontology Molecular Function

RNA polymerase II transcription factor binding [IPI]

Gene Ontology Cellular Component

WormBase Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

52300

6239

Interactors 8
Interactions 8
Network