Caenorhabditis elegans
CYP-13A7
CELE_T10B9.10, ccp-13A7, T10B9.10
cyp-13A7 encodes a homolog of cytochrome P450 proteins; these proteins are membrane proteins with a heme prosthetic group that catalyze the synthesis of steroid hormones (and bile salts), and also detoxify foreign substances (xenobiotic compounds); loss of cyp-13A7 activity in large-scale RNAi screens results in uncoordinated locomotion and decreased and/or slow growth; a cyp-13A7::gfp promoter fusion is induced in the intestine in response to treatment with the antibiotic rifampicin.
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