Caenorhabditis elegans
OIG-4
CELE_R07G3.9, R07G3.9
oig-4 encodes a protein containing a single immunoglobulin domain; OIG-4 is expressed by body wall muscle cells and secreted into the extracellular space where it interacts with, stabilizes, and properly localizes a complex containing levamisole-sensitive acetylcholine receptors (L-AChRs) and the LEV-9 and LEV-10 extracellular and transmembrane, respectively, scaffolding proteins; OIG-4 requires L-AChRs to localize to the synapse, but can partially localize to synaptic regions independently of LEV-9 and LEV-10, suggesting that it could play a role in linking local synaptic cues to clustering of the L-AChR complex; OIG-4 is also expressed in the pm6 pharyngeal muscle and four head neurons.
GO Process (0)
GO Function (0)
GO Component (2)
Gene Ontology Cellular Component
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532021
6239
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