Caenorhabditis elegans
ELC-1
CELE_Y82E9BR.15, Y82E9BR.15
elc-1 encodes an ortholog of mammalian elongin C that appears to be required for proteolysis of germ plasm components (ZF1-containing proteins) in somatic cells, and for regulation of the cell cycle by CUL-2; elongin C forms a complex with (and positively regulates) elongin A, the active subunit of RNA polymerase II elongation factor SIII, and also binds to the von Hippel-Lindau (VHL) tumor suppressor; in yeast, elongin C also interacts with stress response proteins.
GO Process (6)
GO Function (2)
GO Component (0)
Gene Ontology Biological Process
- anterior/posterior axis specification, embryo [IMP]
- embryo development ending in birth or egg hatching [IMP]
- nematode larval development [IMP]
- positive regulation of metaphase/anaphase transition of meiotic cell cycle [IMP]
- receptor-mediated endocytosis [IMP]
- sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation [IMP]
Gene Ontology Molecular Function
Download Curated Data for this Protein
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- Interactors 20
- Interactions 32
- Network