Caenorhabditis elegans

PPT-1

CELE_F44C4.5, F44C4.5
ppt-1 encodes the C. elegans palmitoyl protein thioesterase-1 ortholog; by homology PPT-1 is predicted to function in degradation of palmitoylated proteins and ppt-1 mutations result in loss of enzymatic activity from mixed-stage extracts; in C. elegans, ppt-1 activity is essential for mitochondrial organization and biogenesis in neuronal and muscle cells, as well as for proper timing of the onset of both the L4-to-adult molt and egg laying; ppt-1 is also required for normal egg-laying behavior and for a fully normal adult
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