CELE_AH6.10, AH6.10

sra-6 encodes a seven-transmembrane chemosensory receptor; an sra-6::GFP fusion reporter is expressed in the ASH (strongly) and ASI (weakly) amphid sensory neurons, the PVQ interneurons, and in the SPD and SPV male spicule neurons; sra-6 expression in the ASH neurons is positively regulated by KIN-29, a serine/threonine kinase, acting through the HDA-4 class II histone deacetylase and the MEF-2 MADS domain transcription factor; in addition, maintenance of sra-6::gfp expression in the ASH and ASI requires activity of the DAF-7/TGF-beta signaling pathway.

56270

6239