Caenorhabditis elegans


CELE_T12F5.4, T12F5.4
lin-59 encodes a SET domain-containing protein that is most closely related to the ASH1 group of histone-lysine N-methyltransferases; lin-59 was originally identified in screens for mutations that disrupt male tail development and subsequently was shown to be an essential gene required for development and fate specification of a number of different cells types, including those of the male tail, male and hermaphrodite hindgut, and egg-laying system; lin-59 has been shown to positively regulate expression of at least four genes: cdh-3, egl-5, mab-5, and nac-2; a lin-59::gfp reporter fusion is first expressed during the proliferative stage of embryonic development and expression continues, in most cells, throughout larval development and adulthood.

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WormBase | Entrez Gene | RefSeq | UniprotKB
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