The Arabidopsis BODENLOS gene encodes an auxin response protein inhibiting MONOPTEROS-mediated embryo patterning.

ZMBP, Entwicklungsgenetik, Universitaet Tuebingen, D-72076 Tuebingen, Federal Republic of Germany.
Developmental responses to the plant hormone auxin are thought to be mediated by interacting pairs from two protein families: short-lived inhibitory IAA proteins and ARF transcription factors binding to auxin-response elements. monopteros mutants lacking activating ARF5 and the auxin-insensitive mutant bodenlos fail to initiate the root meristem during early embryogenesis. Here we show that the bodenlos phenotype results from an amino-acid exchange in the conserved degradation domain of IAA12. BODENLOS and MONOPTEROS interact in the yeast two-hybrid assay and the two genes are coexpressed in early embryogenesis, suggesting that BODENLOS inhibits MONOPTEROS action in root meristem initiation.
Mesh Terms:
Arabidopsis, Arabidopsis Proteins, Base Sequence, DNA Primers, DNA-Binding Proteins, Gene Expression Regulation, Genes, Plant, Phenotype, Promoter Regions, Genetic, Seeds, Transcription Factors
Genes Dev. Jul. 01, 2002; 16(13);1610-5 [PUBMED:12101120]
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