EIN3-dependent regulation of plant ethylene hormone signaling by two arabidopsis F box proteins: EBF1 and EBF2.
The plant hormone ethylene regulates a wide range of developmental processes and the response of plants to stress and pathogens. Genetic studies in Arabidopsis led to a partial elucidation of the mechanisms of ethylene action. Ethylene signal transduction initiates with ethylene binding at a family of ethylene receptors and terminates ... in a transcription cascade involving the EIN3/EIL and ERF families of plant-specific transcription factors. Here, we identify two Arabidopsis F box proteins called EBF1 and EBF2 that interact physically with EIN3/EIL transcription factors. EBF1 overexpression results in plants insensitive to ethylene. In contrast, plants carrying the ebf1 and ebf2 mutations display a constitutive ethylene response and accumulate the EIN3 protein in the absence of the hormone. Our work places EBF1 and EBF2 within the genetic framework of the ethylene-response pathway and supports a model in which ethylene action depends on EIN3 protein stabilization.
Mesh Terms:
Arabidopsis, Arabidopsis Proteins, Cell Nucleus, DNA, Complementary, Ethylenes, F-Box Proteins, Gene Expression Regulation, Plant, Molecular Sequence Data, Nuclear Proteins, Phenotype, Receptors, Cell Surface, SKP Cullin F-Box Protein Ligases, Seedling, Sequence Homology, Amino Acid, Sequence Homology, Nucleic Acid, Signal Transduction, Transcription Factors
Arabidopsis, Arabidopsis Proteins, Cell Nucleus, DNA, Complementary, Ethylenes, F-Box Proteins, Gene Expression Regulation, Plant, Molecular Sequence Data, Nuclear Proteins, Phenotype, Receptors, Cell Surface, SKP Cullin F-Box Protein Ligases, Seedling, Sequence Homology, Amino Acid, Sequence Homology, Nucleic Acid, Signal Transduction, Transcription Factors
Cell
Date: Dec. 12, 2003
PubMed ID: 14675533
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