Brassinosteroids regulate dissociation of BKI1, a negative regulator of BRI1 signaling, from the plasma membrane.
Brassinosteroids, the steroid hormones of plants, are perceived at the plasma membrane by a leucine-rich repeat receptor serine/threonine kinase called BRI1. We report a BRI1-interacting protein, BKI1, which is a negative regulator of brassinosteroid signaling. Brassinosteroids cause the rapid dissociation of BKI1-yellow fluorescent protein from the plasma membrane in a ... process that is dependent on BRI1-kinase. BKI1 is a substrate of BRI1 kinase and limits the interaction of BRI1 with its proposed coreceptor, BAK1, suggesting that BKI1 prevents the activation of BRI1.
Mesh Terms:
Amino Acid Sequence, Arabidopsis, Arabidopsis Proteins, Cell Membrane, Cholestanols, Gene Expression Regulation, Plant, Meristem, Molecular Sequence Data, Nuclear Proteins, Phosphorylation, Plants, Genetically Modified, Protein Binding, Protein Kinases, Protein Structure, Tertiary, RNA Interference, Recombinant Fusion Proteins, Signal Transduction, Steroids, Heterocyclic, Two-Hybrid System Techniques
Amino Acid Sequence, Arabidopsis, Arabidopsis Proteins, Cell Membrane, Cholestanols, Gene Expression Regulation, Plant, Meristem, Molecular Sequence Data, Nuclear Proteins, Phosphorylation, Plants, Genetically Modified, Protein Binding, Protein Kinases, Protein Structure, Tertiary, RNA Interference, Recombinant Fusion Proteins, Signal Transduction, Steroids, Heterocyclic, Two-Hybrid System Techniques
Science
Date: Aug. 25, 2006
PubMed ID: 16857903
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